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There is definitely a connection between the eagle and the serpent throughout.
The Eagle Nebula is within the Serpens constellation.
The staff symbolism can also be seen with the winged staff, or caduceus, that also has snakes intertwined around it.
Now, the staff symbolism can be seen from two sources with the greeks. One is Asclepius and the other Hermes.
Here is some information that I found while doing some research on all of this...
The Greeks identified him as Asclepius, the god of medicine. Asclepius was the son of Apollo and Coronis (although some say that his mother was Arsinoë). The story goes that Coronis two-timed Apollo by sleeping with a mortal, Ischys, while she was pregnant by Apollo. A crow brought Apollo the unwelcome news, but instead of the expected reward the crow, which until then had been snow-white, was cursed by Apollo and turned black.
In a rage of jealousy, Apollo shot Coronis with an arrow. Rather than see his child perish with her, Apollo snatched the unborn baby from its mother’s womb as the flames of the funeral pyre engulfed her, and took the infant to Chiron, the wise centaur (represented in the sky by the constellation Centaurus).
Chiron raised Asclepius as his own son, teaching him the arts of healing and hunting. Asclepius became so skilled in medicine that not only could he save lives, he could also raise the dead. On one occasion in Crete, Glaucus, the young son of King Minos, fell into jar of honey and drowned while at play. As Asclepius contemplated the body of Glaucus, a snake slithered towards it. He killed the snake with his staff; then another snake came along with a herb in its mouth and placed it on the body of the dead snake, which magically returned to life. Asclepius took the same herb and laid it on the body of Glaucus, who too was magically resurrected. (Robert Graves suggests that the herb was mistletoe, which the ancients thought had great regenerative properties, but perhaps it was actually willow bark, the source of salicylic acid, the active ingredient in aspirin.) Because of this incident, says Hyginus, Ophiuchus is shown in the sky holding a snake, which became the symbol of healing from the fact that snakes shed their skin every year and are thus seemingly reborn.
Side Note: In Greek mythology, Minos (in Greek Μίνως, genitive Μίνωος) was a mythical king of the island of Crete, son of Zeus and Europa. After his death, Minos became a judge of the dead in Hades. The Minoan civilization has been named after him. By his wife, Pasiphaë, he fathered Ariadne, Androgeus, Deucalion, Phaedra, Glaucus, Catreus, Acacallis, and many others.
Others, though, say that Asclepius received from the goddess Athene the blood of Medusa the Gorgon. The blood that flowed from the veins on her left side was a poison, but the blood from the right side could raise the dead.
Someone else supposedly resurrected by Asclepius was Hippolytus, son of Theseus, who died when he was thrown from his chariot (some identify him with the constellation Auriga, the Charioteer). Reaching for his healing herbs, Asclepius touched the youth’s chest three times, uttering healing words, and Hippolytus raised his head.
Hades, god of the Underworld, began to realize that the flow of dead souls into his domain would soon dry up if this technique became widely known. He complained to his brother god Zeus who struck down Asclepius with a thunderbolt. Apollo was outraged at this harsh treatment of his son and retaliated by killing the three Cyclopes who forged Zeus’ thunderbolts. To mollify Apollo, Zeus made Asclepius immortal (in the circumstances he could hardly bring him back to life again) and set him among the stars as the constellation Ophiuchus.
The brightest star in Ophiuchus is second-magnitude Alpha Ophiuchi, called Rasalhague from the Arabic meaning ‘the head of the serpent collector’. Beta Ophiuchi is called Cebalrai from the Arabic for ‘the shepherd’s dog’; the Arabs visualized a shepherd (the star Alpha Ophiuchi) along with his dog and some sheep in this area.
Delta and Epsilon Ophiuchi are called Yed Prior and Yed Posterior. These are compound names, formed from the Arabic al-yad, meaning ‘hand’, with the Latin words Prior and Posterior added to give names meaning the ‘leading’ and ‘following’ part of the hand.
Side Note: Leto - In the Olympian scheme of things, Zeus is the father of her twins, Apollo and Artemis, the Letoides.
In Roman mythology her equivalent, as mother of Apollo and Diana, is Latona.
.....As the patron of Delphi ("Pythian Apollo"), Apollo was an oracular god. He was the prophetic deity of the Delphic Oracle.....
Side Note: The name of the Pythia derived from Pytho, which in myth was the original name of Delphi. The Greeks derived this place-name from the verb pythein (πύθειν, "to rot"), used of the decomposition of the body of the monstrous serpent Python after she was slain by Apollo.[
.....Apollo also had dominion over colonists, over medicine (mediated through his son Asclepius).....
.....Apollo is known in Greek-influenced Etruscan mythology as Apulu. In Roman mythology he is known as Apollo and increasingly, especially during the third century BC, as Apollo Helios he became identified with Sol, the Sun. In Hellenistic times, Apollo became conflated with Helios, god of the sun, and his sister similarly equated with Selene, goddess of the moon.....
.....Animals sacred to Apollo included.....griffins, mythical eagle-lion hybrids of Eastern origin.....
.....Apollo, the eternal beardless kouros himself, had the most prominent male relationships of all the Greek Gods. That was to be expected from a god who was god of the palaestra, the athletic gathering place for youth who all competed in the nude, a god said to represent the ideal educator and therefore the ideal erastes, or lover of a boy (Sergent, p.102). All his lovers were younger than him, in the style of the Greek pederastic relationships of the time.....
Apollo and the birth of Hermes
Hermes was born on Mount Cyllene in Arcadia. The story is told in the Homeric Hymn to Hermes. His mother, Maia, had been secretly impregnated by Zeus. Maia wrapped the infant in blankets but Hermes escaped while she was asleep. Hermes ran to Thessaly, where Apollo was grazing his cattle. The infant Hermes stole a number of his cows and took them to a cave in the woods near Pylos, covering their tracks. In the cave, he found a tortoise and killed it, then removed the insides. He used one of the cow's intestines and the tortoise shell and made the first lyre. Apollo complained to Maia that her son had stolen his cattle, but Hermes had already replaced himself in the blankets she had wrapped him in, so Maia refused to believe Apollo's claim. Zeus intervened and, claiming to have seen the events, sided with Apollo. Hermes then began to play music on the lyre he had invented. Apollo, a god of music, fell in love with the instrument and offered to allow exchange of the cattle for the lyre. Hence, Apollo became a master of the lyre and Hermes invented a kind of pipes-instrument called a syrinx.
Later, Apollo exchanged a caduceus for a syrinx from Hermes.
Side Note: Maia in Greek mythology, was the eldest of the Pleiades.....She and her sisters were pursued by Orion
And of course, we have the connection with the Egyptian God Thoth...
.....His chief shrine was at Khemennu, where he was the head of the local company of gods, later renamed Hermopolis by the Greeks (in reference to him through the Greeks' interpretation that he was the same as Hermes) and Eshmûnên by the Arabs.....
.....He was considered the heart and tongue of Ra as well as the means by which Ra's will was translated into speech. He has also been likened to the Logos of Plato and the mind of God. (see The All) In the Egyptian mythology, he has played many vital and prominent roles, including being one of the two gods (the other being Ma'at) who stood on either side of Ra's boat. He has further been involved in arbitration, magic, writing, science, and the judging of the dead.....
Side Note: The All (also called The One, The Absolute, The Great One, The Creator, The Supreme Mind, The Supreme Good, The Father, and The Universal Mother) is the Hermetic or panentheistic view of God, which is that everything that is, or at least that can be experienced, collectively makes up The All. One Hermetic maxim states, "While All is in The All, it is equally true that The All is in All." The All can also seen to be hermaphroditic, possessing both masculine and feminine qualities in equal part .....
.....In 1975, Summum, an esoteric organization whose philosophy also includes the natural principles described in The Kybalion , put forth an explanation behind The All's existence and claims the explanation came from "Summa Individuals" , beings who appear to be what The Kybalion describes as "Unseen Divinities" that intervene and assist with human affairs.....
.....Thoth was also known by specific aspects of himself, for instance the moon god A'ah-Djehuty, representing the moon for the entire month.....
.....Further, the Greeks related Thoth to their god Hermes due to his similar attributes and functions. One of Thoth 's titles, "Three times great, great" (see Titles) was translated to the Greek τρισμεγιστος (Trismegistos) making Hermes Trismegistus.....
.....E. A. Wallis Budge, however, thought Egyptian religion to be primarily monotheistic where all the gods and goddesses were aspects of the God Ra, similar to the Trinity in Christianity and devas in Hinduism. In this view, Thoth would be the aspect of Ra which the Egyptian mind would relate to the heart and tongue.....
.....Thoth has played a prominent role in many of the Egyptian myths. Displaying his role as arbitrator, he had overseen the three epic battles between good and evil.....
.....Thoth was also prominent in the Osiris myth, being of great aid to Isis. After Isis gathered together the pieces of Osiris' dismembered body, he gave her the words to resurrect him so she could be impregnated and bring forth Horus, named for his uncle. When Horus was slain, Thoth gave the formulae to resurrect him as well. Similar to God speaking the words to create the heavens and Earth in Judeo-Christian mythology, Thoth, being the god who always speaks the words that fulfill the wishes of Ra, spoke the words that created the heavens and Earth in Egyptian mythology.....
.....Thoth, like many Egyptian gods and nobility, held many titles. Among these were "Scribe of Ma'at in the Company of the Gods", "Lord of Ma'at", "Lord of Divine Words", "Judge of the Two Combatant Gods", "Judge of the Rekhekhui, the pacifier of the Gods, who Dwelleth in Unnu, the Great God in the Temple of Abtiti", "Twice Great", "Thrice Great", and "Three Times Great, Great".....
For further reading on Thoth, here is a link that shows other connections to the ouroboros, Quetzalcoatl, Viracocha, Nimrod, etc. There is also a link to "The Emerald Tablets of Thoth" at the bottom of the page...
So, Asclepius/Hermes/Thoth, are the same representation of Ophiuchus, and Ophiuchus is positioned in the Serpens constellation, which consists of Caput Draconis and Cauda Draconis, who are possibly the two combatants in "The War of the Gods".