I've seen no mention of "the league" thus far, check that out if you haven't already.
Not knowing anything about football will not keep you from enjoying it.
A new one that might pique your interests is "Legit" which is also produced by fx.
It stars Jim Jefferies, a great stand up comedian you might be familiar with. So far it hasn't been that spectacular (possibly because the best episodes I was familiar with via his stand up already) but it has potential.